Biology, Free Full-Text
Por um escritor misterioso
Last updated 24 dezembro 2024
In addition to representing a significant part of the natural background radiation exposure, α-particles are thought to be a powerful tool for targeted radiotherapy treatments. Understanding the molecular mechanisms of recognition, signaling, and repair of α-particle-induced DNA damage is not only important in assessing the risk associated with human exposure, but can also potentially help in identifying ways of improving the efficacy of radiation treatment. α-particles (He2+ ions), as well as other types of ionizing radiation, and can cause a wide variety of DNA lesions, including DNA double-strand breaks (DSBs). In mammalian cells, DNA DSBs can be repaired by two major pathways: non-homologous end-joining (NHEJ) and homologous recombination (HR). Here, we investigated their dynamics in mouse NIH-3T3 cells through the recruitment of key proteins, such as the KU heterodimer for NHEJ and RAD51 for HR upon localized α-particle irradiation. To deliver α-particles, we used the MIRCOM microbeam, which allows targeting of subnuclear structures with submicron accuracy. Using mouse NIH-3T3 cells, we found that the KU heterodimer is recruited much earlier at DNA damage sites marked by H2AX phosphorylation than RAD51. We also observed that the difference in the response of the KU complex and RAD51 is not only in terms of time, but also in function of the chromatin nature. The use of a microbeam such as MIRCOM, represents a powerful tool to study more precisely the cellular response to ionizing irradiation in a spatiotemporal fashion at the molecular level.
Hair Biology Full and Vibrant Volumizing Shampoo for Fine, Thin, Flat Hair, 12.8 oz
Bold biology font Royalty Free Vector Image - VectorStock
SOLUTION: Biology notes - Studypool
Nature Reviews Molecular Cell Biology on X: From May cover Challenges and directions in studying cell–cell communication by #ExtracellularVesicles @DaveCarter1234 @guillaume_niel @VaderPieter Clayton Lambert & Raposo #EVsAreCool FREE pdf: https
Basic Biology Activities & Jigsaws – ORB Education US
Biology the easy way : Edwards, Gabrielle I : Free Download, Borrow, and Streaming : Internet Archive
Stream [DOWNLOAD] ⚡️ PDF BRS Biochemistry, Molecular Biology, and Genetics (Board Review Series) Full Books from Gusto Celo
Educart NEET BIOLOGY 35 Years Chapterwise Topicwise Solved Papers 2023 (With FREE Abhyaas Full Mock papers inside)AIIMS & NEET Books
Premium Vector Biology 3d text effect vector download
Free High School Biology – Easy Hard Science
2,165 Biology Books Stock Photos - Free & Royalty-Free Stock Photos from Dreamstime
Unit 1 - Biology Basics - Test ⋆
Recomendado para você
-
Smart TV Club APK for Android Download24 dezembro 2024
-
Large-scale international volleyball competition in “bubble” under the COVID-19 pandemic - ScienceDirect24 dezembro 2024
-
Serato ITCH 2.2.2, Scratch Live 2.4.3 & Video 1.124 dezembro 2024
-
Syntheses of three-dimensional catenanes under kinetic control24 dezembro 2024
-
Moving towards a Treatable Traits model of care for the management of obstructive airways diseases - ScienceDirect24 dezembro 2024
-
IJERPH, Free Full-Text24 dezembro 2024
-
Govee Home 5.9.10 Free Download24 dezembro 2024
-
Host–Guest Complexation of Bisporphyrin Cleft and Electron-Deficient Aromatic Guests24 dezembro 2024
-
Human oral lectin ZG16B acts as a cell wall polysaccharide probe to decode host–microbe interactions with oral commensals24 dezembro 2024
-
Synthesis of 3,4,5-Trisubstituted-1,2,4-triazoles24 dezembro 2024
você pode gostar
-
Buy Wholesale China Game Driving Simulator New Product 4d Driving Car Driving Simulator Car Racing Games For Kids & Game Driving Simulator New Product 4d Driving Car at USD 960024 dezembro 2024
-
Hantai Anime Girl Figure High School DxD Born Himejima Akeno/Rias Gremory S-Style 1/12 Model Toys Action Figure Collection Anime Character with Retail Box (Both) : Toys & Games24 dezembro 2024
-
Capra, Bleach True Fanon Wiki24 dezembro 2024
-
Geweldig: Club Brugge-fans laten zich tijdens coronacrisis van24 dezembro 2024
-
Veja como derrotar e capturar um Mega Salamence em Pokémon GO24 dezembro 2024
-
what do I need to enter?? : r/SCP24 dezembro 2024
-
The Witcher 2 Enhanced Edition Prima Official Strategy Guide (App 206783) · SteamDB24 dezembro 2024
-
Read Fantasy Bishoujo Juniku Ojisan To Chapter 2 on Mangakakalot24 dezembro 2024
-
Stream Rin Nohara Listen to Naruto playlist online for free on SoundCloud24 dezembro 2024
-
How To Get Started With Chess (If You Don't Know The Rules)24 dezembro 2024