Biomedicines, Free Full-Text
Por um escritor misterioso
Last updated 17 outubro 2024
Alpha-synuclein’s role in diseases termed “synucleinopathies”, including Parkinson’s disease, has been well-documented. However, after over 25 years of research, we still do not fully understand the alpha-synuclein protein and its role in disease. In vitro cellular models are some of the most powerful tools that researchers have at their disposal to understand protein function. Advantages include good control over experimental conditions, the possibility for high throughput, and fewer ethical issues when compared to animal models or the attainment of human samples. On the flip side, their major disadvantages are their questionable relevance and lack of a “whole-brain” environment when it comes to modeling human diseases, such as is the case of neurodegenerative disorders. Although now, with the advent of pluripotent stem cells and the ability to create minibrains in a dish, this is changing. With this review, we aim to wade through the recent alpha-synuclein literature to discuss how different cell culture setups (immortalized cell lines, primary neurons, human induced pluripotent stem cells (hiPSCs), blood–brain barrier models, and brain organoids) can help us understand aggregation pathology in Parkinson’s and other synucleinopathies.
Biomedicines An Open Access Journal from MDPI
Biomedicines, Free Full-Text
Live Cd Pt Br Get File - Colaboratory
Crack Asd 2014 Get File - Colaboratory
Biomolecules and Biomedicine
Systems-level analyses of protein-protein interaction network
Biomedicines (ISSN 2227-9059, IF: 6.081) Questionnaire
NMR in Biomedicine - Wiley Online Library
Cdl-Buch Illinois Herunterladen - Colaboratory
Biomedicines, Free Full-Text
Changes in nanomechanical properties of single neuroblastoma cells
Biomedicine & Pharmacotherapy, Journal
Biomedicines An Open Access Journal from MDPI
Biodistribution of mRNA COVID-19 vaccines in human breast milk
Recomendado para você
-
Você precisa conhecer Jesus17 outubro 2024
-
Advogado Correspondente em Ipatinga, MG - Kelly Godoy Coelho17 outubro 2024
-
RESULTADO DO CONCURSO PÚBLICO – EDITAL Nº 02/2022 -RESULTADO FINAL DA PROVA OBJETIVA E AVALIAÇÃO DE TÍTULOS E PEÇA PROCESSUAL - Prefeitura de Embu-Guaçu17 outubro 2024
-
Miriam Leitão é a +Premiada Jornalista da História na Região Sudeste17 outubro 2024
-
Gustavo Toledo Kelly - Apresentador - Record News17 outubro 2024
-
Teixeira Coelho (1944-2022) - A Terra é Redonda17 outubro 2024
-
Monalisa dos Reis Aguiar17 outubro 2024
-
Frontiers The interaction between dietary fiber and gut17 outubro 2024
-
Morsyleide ROSA, Senior Researcher, PhD17 outubro 2024
-
Papo de Fotógrafo17 outubro 2024
você pode gostar
-
Review de Yahari Ore no Seishun Love Come wa Machigatteiru. Kan (Oregairu) 3ª Temporada - Lacradores Desintoxicados17 outubro 2024
-
Lucky Blocks Rank - Out now! 🍀🤞17 outubro 2024
-
One Piece Episode 1 - Watch One Piece E01 Online17 outubro 2024
-
APK Frases Evangélicas Em Inglês untuk Muat Turun Android17 outubro 2024
-
ArtStation - Jotaro Kujo17 outubro 2024
-
Fact Check: Is there any crossplay option in GTA Online?17 outubro 2024
-
Reel Desire (Yggdrasil) Slot Review - 💎AboutSlots17 outubro 2024
-
Shingeki No Kyojin - Eu sou o titã encouraçado, e ele é o17 outubro 2024
-
Sailor Moon Crystal- New Transformation, with Old Music (DiC/Season 2 Version)17 outubro 2024
-
Classroom of the Elite Season 2 Force without wisdom falls of its own weight. - Watch on Crunchyroll17 outubro 2024