Biosensors, Free Full-Text
Por um escritor misterioso
Last updated 17 outubro 2024
Liver fibrosis is a key pathological precondition for hepatocellular carcinoma in which the severity is confidently correlated with liver cancer. Liver fibrosis, characterized by gradual cell loss and excessive extracellular matrix deposition, can be reverted if detected at the early stage. The gold standard for staging and diagnosis of liver fibrosis is undoubtedly biopsy. However, this technique needs careful sample preparation and expert analysis. In the present work, an ex vivo, minimally destructive, label-free characterization of liver biopsies is presented. Through a custom-made experimental setup, liver biopsies of bile-duct-ligated and sham-operated mice were measured at 8, 15, and 21 days after the procedure. Changes in impedance were observed with the progression of fibrosis, and through data fitting, tissue biopsies were approximated to an equivalent RC circuit model. The model was validated by means of 3D hepatic cell culture measurement, in which the capacitive part of impedance was proportionally associated with cell number and the resistive one was proportionally associated with the extracellular matrix. While the sham-operated samples presented a decrease in resistance with time, the bile-duct-ligated ones exhibited an increase in this parameter with the evolution of fibrosis. Moreover, since the largest difference in resistance between healthy and fibrotic tissue, of around 2 kΩ, was found at 8 days, this method presents great potential for the study of fibrotic tissue at early stages. Our data point out the great potential of exploiting the proposed needle setup in clinical applications.
Cell-free biosensors for rapid detection of water contaminants
Cell-Free Biosensors: Synthetic Biology Without Borders
Recent advances in graphene-based biosensor technology with applications in life sciences, Journal of Nanobiotechnology
Metal Nanoparticles‐Enhanced Biosensors: Synthesis, Design and Applications in Fluorescence Enhancement and Surface‐enhanced Raman Scattering - Yaraki - 2020 - Chemistry – An Asian Journal - Wiley Online Library
Biosensing with Fluorescent Carbon Nanotubes - Ackermann - 2022 - Angewandte Chemie International Edition - Wiley Online Library
Frontiers Development of Point-of-Care Biosensors for COVID-19
Understanding Statistical Error A Primer For Biologists Download - Colaboratory
Biosensors, Free Full-Text
Biosensors, Free Full-Text
Synthetic biology enables field-deployable biosensors for water contaminants - ScienceDirect
Cell-free biosensors for biomedical applications - ScienceDirect
Recent advances in graphene-based biosensor technology with applications in life sciences, Journal of Nanobiotechnology
A Review of Piezoelectric and Magnetostrictive Biosensor Materials for Detection of COVID‐19 and Other Viruses - Narita - 2021 - Advanced Materials - Wiley Online Library
Biosensors for healthcare: current and future perspectives: Trends in Biotechnology
Recomendado para você
-
Mais alto da atual NBA, sérvio Boban Marjanović vive assassino em John Wick 3, de Keanu Reeves, basquete17 outubro 2024
-
Wembanyama impressiona ao lado de Mbappé, mas não será o mais alto da história da NBA - Jogada - Diário do Nordeste17 outubro 2024
-
Back 2 Back 🇵🇹🇧🇷 on X: Pense duas vezes antes de sair NA MÃO com Boban Marjanovic 😅 / X17 outubro 2024
-
Boban diz que deveria estar no Slam Dunk Contest17 outubro 2024
-
Camisa 23 on X: MANO DO CÉU O tamanho da mão do Boban Marjanovic em comparação às cartas de Uno ASSUSTADOR, P*TA QUE PARIU 😳 / X17 outubro 2024
-
NBA: Harden bate marca histórica em Clippers x Warriors17 outubro 2024
-
NBA aprova política que proíbe equipas de poupar estrelas - NBA - Jornal Record17 outubro 2024
-
Marcus Morris abre o coração sobre Joel Embiid: “Melhor jogador que…”17 outubro 2024
-
Frontiers The Making of Calibration Sausage Exemplified by Recalibrating the Transcriptomic Timetree of Jawed Vertebrates17 outubro 2024
-
Graphene-Based Material-Mediated Immunomodulation in Tissue Engineering and Regeneration: Mechanism and Significance17 outubro 2024
você pode gostar
-
2 IN 1 SONIC THE HEDGEHOG BOUNCE HOUSE Party Inflatable - Bounce17 outubro 2024
-
🐺Mikhail Jirov🧛🏻♂️17 outubro 2024
-
Marvel's Spider-Man Remastered ganha página no Steam17 outubro 2024
-
Play Chess Online: Master Chess Openings with Better Understanding17 outubro 2024
-
I Wish Roblox Guests Come Back by Thg04 on Newgrounds17 outubro 2024
-
Ler BD: 10/1317 outubro 2024
-
Jogo Diverso Bichinhos Equilibristas Pais e Filhos 791707 na Papelaria Art Nova17 outubro 2024
-
Collectibles MM2 Godly Laser Gun - Game Items - Gameflip17 outubro 2024
-
Full Metal Alchemist anime IS BETTER THAN FMA: Brotherhood17 outubro 2024
-
Pin by Valeria Salcedo on madness combat17 outubro 2024