Pathogens, Free Full-Text

In 1973, the National Rabies Program was created in Brazil through an agreement between the Ministry of Health and Agriculture. Since its beginning, it developed integrated action through access to free post-exposure prophylaxis (PEP) for people at risk, dog vaccination campaigns, a joint surveillance system, and awareness. This study aims to describe human rabies in Brazil under the One Health perspective in recent decades, including achievements in the control of dog-mediated cases and challenges in human cases transmitted by wild animals. This paper also explores possible drivers of human rabies in the Northeast Region with half of the cases. The first part of this study was descriptive, presenting data and examples by periods. Statistical analysis was performed in the last period (2010–2022) to explore possible drivers. Dog-mediated human cases decreased from 147 to 0, and dog cases decreased from 4500 to 7. A major challenge is now human cases transmitted by wild animals (bats, non-human primates, and wild canids). Most current human cases occur in municipalities with a tropical and subtropical moist broadleaf forest biome and a Gini index higher than 0.5. In the multivariable analysis, an association with temperature was estimated (OR = 1.739; CI95% = 1.181–2.744), and primary healthcare coverage (OR = 0.947; CI95% = 0.915–0.987) was identified as a protector. It is possible to significantly reduce the number of dog-mediated human rabies cases through the efforts presented. However, Brazil has wildlife variants of the rabies virus circulating. The association of human cases with higher temperatures in the Northeast is a concern with climate change. To reduce human cases transmitted by wild animals, it is important to continue distributing free PEP, especially in remote at-risk areas in the Region, and to increase awareness.

A culture-free biphasic approach for sensitive and rapid detection of pathogens in dried whole-blood matrix

Detection of Viable Pathogens Using Label-Free Electrical Detection of Nucleic Acid Amplification : LIBNA

Pathogens Vectors & Illustrations for Free Download

Global mortality associated with 33 bacterial pathogens in 2019: a systematic analysis for the Global Burden of Disease Study 2019 - The Lancet

Nutritional immunity: the battle for nutrient metals at the host–pathogen interface

Pathogens Packet - Bacteria Viruses Protozoa Fungi Parasites and Prions - Homeschool Den

Pathogens, Free Full-Text

Pathogens, Definition, Types & Examples - Video & Lesson Transcript

Pathogens, Free Full-Text

Ecological and socioeconomic factors associated with the human burden of environmentally mediated pathogens: a global analysis - The Lancet Planetary Health