GPC2-CAR T cells tuned for low antigen density mediate potent

Pediatric cancers often mimic fetal tissues and express proteins normally silenced postnatally that could serve as immune targets. We developed T cell…

Mechanisms of Resistance and Treatment of Relapse after CAR T-cell Therapy for Large B-cell Lymphoma and Multiple Myeloma - Transplantation and Cellular Therapy, Official Publication of the American Society for Transplantation and

CAR T cells targeting tumor-associated exons of glypican 2 regress neuroblastoma in mice - ScienceDirect

Frontiers Fine-tuning the antigen sensitivity of CAR T cells: emerging strategies and current challenges

GPC2-CAR T cells tuned for low antigen density mediate potent activity against neuroblastoma without toxicity - ScienceDirect

Reprogramming T cell differentiation and exhaustion in CAR-T cell therapy, Journal of Hematology & Oncology

CAR T cells targeting tumor-associated exons of glypican 2 regress neuroblastoma in mice. - Abstract - Europe PMC

Development of GPC2-directed chimeric antigen receptors using mRNA for pediatric brain tumors

Development of GPC2-directed chimeric antigen receptors using mRNA for pediatric brain tumors. - Abstract - Europe PMC

CD276-CAR T cells and Dual-CAR T cells targeting CD276/FGFR4 promote rhabdomyosarcoma clearance in orthotopic mouse models, Journal of Experimental & Clinical Cancer Research

Recent advances and discoveries in the mechanisms and functions of CAR T cells

Overcoming on-target, off-tumour toxicity of CAR T cell therapy for solid tumours. - Abstract - Europe PMC

Full article: B7-H3-targeted CAR-T cell therapy for solid tumors

CD276-CAR T cells and Dual-CAR T cells targeting CD276/FGFR4 promote rhabdomyosarcoma clearance in orthotopic mouse models, Journal of Experimental & Clinical Cancer Research