Methodology of the DCCSS later fatigue study: a model to investigate chronic fatigue in long-term survivors of childhood cancer, BMC Medical Research Methodology
Por um escritor misterioso
Last updated 24 outubro 2024
Background A debilitating late effect for childhood cancer survivors (CCS) is cancer-related fatigue (CRF). Little is known about the prevalence and risk factors of fatigue in this population. Here we describe the methodology of the Dutch Childhood Cancer Survivor Late Effect Study on fatigue (DCCSS LATER fatigue study). The aim of the DCCSS LATER fatigue study is to examine the prevalence of and factors associated with CRF, proposing a model which discerns predisposing, triggering, maintaining and moderating factors. Triggering factors are related to the cancer diagnosis and treatment during childhood and are thought to trigger fatigue symptoms. Maintaining factors are daily life- and psychosocial factors which may perpetuate fatigue once triggered. Moderating factors might influence the way fatigue symptoms express in individuals. Predisposing factors already existed before the diagnosis, such as genetic factors, and are thought to increase the vulnerability to develop fatigue. Methodology of the participant inclusion, data collection and planned analyses of the DCCSS LATER fatigue study are presented. Results Data of 1955 CCS and 455 siblings was collected. Analysis of the data is planned and we aim to start reporting the first results in 2022. Conclusion The DCCSS LATER fatigue study will provide information on the epidemiology of CRF and investigate the role of a broad range of associated factors in CCS. Insight in associated factors for fatigue in survivors experiencing severe and persistent fatigue may help identify individuals at risk for developing CRF and may aid in the development of interventions.
Late Effects of Treatment for Childhood Cancer (PDQ®) - NCI
Cancer-related fatigue in childhood cancer survivors: A systematic
Development of a self-management support practice framework for
Cancers, Free Full-Text
Chronic fatigue syndrome: Harvey and Wessely's (bio)psychosocial
PDF) Recommendations for the surveillance of cancer-related
Prevalence and 95% Confidence Intervals of severe and chronic
High Prevalence of Chronic Fatigue in Adult Long-Term Survivors of
PDF) Fatigue trajectories during pediatric ALL therapy are
Late Effects of Treatment for Childhood Cancer (PDQ®) - PDQ Cancer
PDF) Questionnaire- and linkage-based outcomes in Dutch childhood
Sample composition flowchart. LAE = late adverse effects, VER
PDF) Prevalence and risk factors of cancer‐related fatigue in
Risk of cancer following primary care presentation with fatigue: a
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