The Safety of High Dose Labetalol in the Pregnant Population

Hypertension in pregnancy is one of the leading causes of maternal mortality and rapid treatment is critical. Treatment of emergent hypertensive crises in pregnancy is limited to only three medications, one of which is labetalol. Current literature recommends a daily maximum intravenous labetalol dose of 300 mg per day. However, this maximum dose has not been studied in pregnancy where higher doses may be required.

Best Practices for Managing Postpartum Hypertension

Hypertension in Pregnancy

A COMPARATIVE RANDOMISED CONTROLLED PARALLEL GROUP STUDY OF EFFICACY AND TOLERABILITY OF LABETALOL VERSUS METHYLDOPA IN THE TREATMENT OF NEW ONSET HYPERTENSION DURING PREGNANCY

A COMPARATIVE RANDOMISED CONTROLLED PARALLEL GROUP STUDY OF EFFICACY AND TOLERABILITY OF LABETALOL VERSUS METHYLDOPA IN THE TREATMENT OF NEW ONSET HYPERTENSION DURING PREGNANCY

Labetalol - Wikipedia

Complications of Pregnancy: Part II, 2008-02-04

Hypertension Canada's 2018 Guidelines for the Management of Hypertension in Pregnancy - Canadian Journal of Cardiology

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The Safety of High Dose Labetalol in the Pregnant Population

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Doses of antihypertensive drugs in pregnancy

PDF) Oral nifedipine versus intravenous labetalol for severe hypertension during pregnancy: A systematic review and meta-analysis

PDF) Drug Treatment of Hypertension in Pregnancy